PT  - JOURNAL ARTICLE
AU  - Bert B A de Vries
AU  - Hanneke M A van den Boer-van den Berg
AU  - Martinus F Niermeijer
AU  - Aad Tibben
TI  - Dilemmas in counselling females with the fragile X syndrome
AID  - 10.1136/jmg.36.2.167
DP  - 1999 Feb 01
TA  - Journal of Medical Genetics
PG  - 167--170
VI  - 36
IP  - 2
4099  - http://jmg.bmj.com/content/36/2/167.short
4100  - http://jmg.bmj.com/content/36/2/167.full
SO  - J Med Genet1999 Feb 01; 36
AB  - The dilemmas in counselling a mildly retarded female with the fragile X syndrome and her retarded partner are presented. The fragile X syndrome is an X linked mental retardation disorder that affects males and, often less severely, females. Affected females have an increased risk of having affected offspring.  The counselling of this couple was complicated by their impaired comprehension which subsequently impaired their thinking on the different options. The woman became pregnant and underwent CVS, which showed an affected male fetus. The pregnancy was terminated. Whether non-directive counselling for this couple was the appropriate method is discussed and the importance of a system oriented approach, through involving relatives, is stressed.