TY - JOUR T1 - Keratosis follicularis spinulosa decalvans: confirmation of linkage to Xp22.13-p22.2. JF - Journal of Medical Genetics JO - J Med Genet SP - 336 LP - 337 DO - 10.1136/jmg.35.4.336 VL - 35 IS - 4 AU - M E Porteous AU - L Strain AU - L J Logie AU - R M Herd AU - E C Benton Y1 - 1998/04/01 UR - http://jmg.bmj.com/content/35/4/336.abstract N2 - Keratosis follicularis spinulosa decalvans (KFSD) is a rare, X linked disorder with skin and eye involvement (MIM 308800). We have studied a large British family with KFSD using polymorphic markers from Xp21-p23 and obtained a lod score of 2.056 at theta=0 with markers proximal and distal to the KFSD candidate region Xp22.13-p22.2 identified by Oosterwijk et al. Our data confirm the linkage to Xp22.13-p22.2 observed in the previously reported Dutch family, but fail to narrow the candidate interval for the KFSD locus. ER -