RT Journal Article
SR Electronic
T1 "Cutis tricolor": congenital hyper- and hypopigmented macules associated with a sporadic multisystem birth defect: an unusual example of twin spotting?
JF Journal of Medical Genetics
JO J Med Genet
FD BMJ Publishing Group Ltd
SP 676
OP 678
DO 10.1136/jmg.34.8.676
VO 34
IS 8
A1 Happle, R
A1 Barbi, G
A1 Eckert, D
A1 Kennerknecht, I
YR 1997
UL http://jmg.bmj.com/content/34/8/676.abstract
AB An uncommon coexistence of circumscribed hyperpigmentation and hypopigmentation, in close proximity to each other, is described in a 17 years old patient with various other cogenital defects, such as dysmorphic facial appearance, severe kyphoscoliosis, delayed motor development, epileptic seizures, and mental retardation. We suggest the combination of hyper- and hypopigmented cutaneous lesions is an example of allelic twin spotting. Because the skin of this patient showed three different degrees of pigmentation the term "cutis tricolor" is proposed.