PT  - JOURNAL ARTICLE
AU  - R Happle
AU  - G Barbi
AU  - D Eckert
AU  - I Kennerknecht
TI  - "Cutis tricolor": congenital hyper- and hypopigmented macules associated with a sporadic multisystem birth defect: an unusual example of twin spotting?
AID  - 10.1136/jmg.34.8.676
DP  - 1997 Aug 01
TA  - Journal of Medical Genetics
PG  - 676--678
VI  - 34
IP  - 8
4099  - http://jmg.bmj.com/content/34/8/676.short
4100  - http://jmg.bmj.com/content/34/8/676.full
SO  - J Med Genet1997 Aug 01; 34
AB  - An uncommon coexistence of circumscribed hyperpigmentation and hypopigmentation, in close proximity to each other, is described in a 17 years old patient with various other cogenital defects, such as dysmorphic facial appearance, severe kyphoscoliosis, delayed motor development, epileptic seizures, and mental retardation. We suggest the combination of hyper- and hypopigmented cutaneous lesions is an example of allelic twin spotting. Because the skin of this patient showed three different degrees of pigmentation the term "cutis tricolor" is proposed.