TY - JOUR T1 - Further evidence for preaxial hallucal polydactyly as a marker of diabetic embryopathy. JF - Journal of Medical Genetics JO - J Med Genet SP - 261 LP - 263 DO - 10.1136/jmg.34.3.261 VL - 34 IS - 3 AU - J Slee AU - J Goldblatt Y1 - 1997/03/01 UR - http://jmg.bmj.com/content/34/3/261.abstract N2 - Maternal diabetes has an established aetiological link with developmental abnormalities, and the prevalence of major congenital malformations in the offspring of affected women is approximately 4-8%, compared to the general population risk of about 3%. Hallucal polydactyly, particularly with an unusual proximal placement of the extra digit, has been reported as a distinctive anomaly in diabetic embryopathy. We report on a child of a diabetic mother with this unusual form of hallucal polydactyly, together with other skeletal anomalies, confirming that this malformation is a useful clinical marker for the diagnosis of diabetic embryopathy. ER -