RT Journal Article SR Electronic T1 An autosomal recessive syndrome of cleft palate, cardiac defect, genital anomalies, and ectrodactyly (CCGE). JF Journal of Medical Genetics JO J Med Genet FD BMJ Publishing Group Ltd SP 72 OP 74 DO 10.1136/jmg.32.1.72 VO 32 IS 1 A1 Giannotti, A A1 Digilio, M C A1 Mingarelli, R A1 Dallapiccola, B YR 1995 UL http://jmg.bmj.com/content/32/1/72.abstract AB We report a brother and sister affected by a constellation of malformations, including cleft palate, cardiac defect, genital anomalies, and ectrodactyly (CCGE). A similar association has been reported previously by Richieri-Costa and Orquizas in a male patient born to consanguineous parents. An autosomal recessive pattern of inheritance is proposed for this syndrome.