TY - JOUR T1 - Chromosomal localisation of a gene(s) for Turner stigmata on Yp. JF - Journal of Medical Genetics JO - J Med Genet SP - 918 LP - 922 DO - 10.1136/jmg.30.11.918 VL - 30 IS - 11 AU - T Ogata AU - C Tyler-Smith AU - S Purvis-Smith AU - G Turner Y1 - 1993/11/01 UR - http://jmg.bmj.com/content/30/11/918.abstract N2 - Although recent cytogenetic and molecular studies in patients with Turner stigmata are consistent with a gene(s) for Turner stigmata being present on both Xp and Yp, the precise location has not been determined. In this report, we describe a phenotypically female infant with Turner stigmata and a partial Yp deletion and review genotype-phenotype correlations of the putative Turner gene(s) in non-mosaic patients with Y chromosome rearrangements resulting from chromosomal breakage at Yp or Yc (pericentromeric region). The results indicate that the putative Turner gene(s) on Yp is located in the Y specific region from interval 1A1A to interval 2B. In addition, assessment of ZFX/ZFY and RPS4X/RPS4Y in the context of the Turner gene(s) suggests that ZFX/ZFY rather than RPS4X/RPS4Y could be a candidate gene for the Turner stigmata. ER -