RT Journal Article
SR Electronic
T1 Consanguinity, cardiac arrest, hearing impairment, and ECG abnormalities: counselling pitfalls in the Romano-Ward syndrome.
JF Journal of Medical Genetics
JO J Med Genet
FD BMJ Publishing Group Ltd
SP 325
OP 327
DO 10.1136/jmg.30.4.325
VO 30
IS 4
A1 W Reardon
A1 N Lewis
A1 H E Hughes
YR 1993
UL http://jmg.bmj.com/content/30/4/325.abstract
AB Genetic counselling in the autosomal dominant condition of the Romano-Ward syndrome might be assumed to be relatively straightforward. The problems posed by consanguinity, deafness, and subclinical gene carriers in a pedigree with this condition have caused us to reevaluate this view. The diagnostic and management difficulties which may attend this potentially fatal condition are highlighted by our experience with this family.