PT - JOURNAL ARTICLE AU - Harper, P S AU - Newcombe, R G TI - Age at onset and life table risks in genetic counselling for Huntington's disease. AID - 10.1136/jmg.29.4.239 DP - 1992 Apr 01 TA - Journal of Medical Genetics PG - 239--242 VI - 29 IP - 4 4099 - http://jmg.bmj.com/content/29/4/239.short 4100 - http://jmg.bmj.com/content/29/4/239.full SO - J Med Genet1992 Apr 01; 29 AB - Age related genetic risk data for carrying the gene for Huntington's disease in relatives at risk, based on a previously documented life table approach, are presented in a form allowing ready access for use in genetic counselling. Figures are given for first degree relatives and for second degree relatives showing varying age combinations of consultand and intervening parent at risk. Data are also given for the risk of developing Huntington's disease over varying finite periods in relation to age. The availability of this information in tabular form should help those involved in genetic counselling for this disorder in providing accurate risk estimates to relatives; the data are also of importance for combination with genotype information in predictive testing.