RT Journal Article SR Electronic T1 Carrier estimations in Duchenne muscular dystrophy families in Northern Ireland using RFLP analysis. JF Journal of Medical Genetics JO J Med Genet FD BMJ Publishing Group Ltd SP 101 OP 104 DO 10.1136/jmg.27.2.101 VO 27 IS 2 A1 Kelly, E D A1 Graham, C A A1 Hill, A J A1 Nevin, N C YR 1990 UL http://jmg.bmj.com/content/27/2/101.abstract AB Intragenic RFLP analysis was used to provide carrier risk estimations on 100 possible female carriers from 22 Duchenne muscular dystrophy families. This enabled 78% of possible carriers to be assigned high or low risks (greater than 90% or less than 10%) as opposed to 26% assigned low risk on pedigree data alone. When a single polymorphism is not informative the use of haplotype analysis for carrier estimations is illustrated for one family.