PT - JOURNAL ARTICLE AU - Lehesjoki, A E AU - Sankila, E M AU - Miao, J AU - Somer, M AU - Salonen, R AU - Rapola, J AU - de la Chapelle, A TI - X linked neonatal myotubular myopathy: one recombination detected with four polymorphic DNA markers from Xq28. AID - 10.1136/jmg.27.5.288 DP - 1990 May 01 TA - Journal of Medical Genetics PG - 288--291 VI - 27 IP - 5 4099 - http://jmg.bmj.com/content/27/5/288.short 4100 - http://jmg.bmj.com/content/27/5/288.full SO - J Med Genet1990 May 01; 27 AB - A three generation family with X linked myotubular myopathy (MTM1) was studied with several polymorphic markers from the distal long arm of the X chromosome. A recombination between the disease gene and four markers (loci DXS52, DXS134, DXS15, F8C) from the Xq28 cluster was detected. A new polymorphic marker (U6.2) defining the locus DXS304 in the Xq27-28 region proximal to the Xq28 cluster did not show any recombination with MTM1. These results suggest the following order of loci in distal Xq: cen-DXS42-DXS105-(DXS304, MTM1)-(DXS52, DXS134, DXS15, F8C)-tel.