PT  - JOURNAL ARTICLE
AU  - Q A Alsaleh
AU  - A S Teebi
TI  - Autosomal recessive epidermolytic palmoplantar keratoderma.
AID  - 10.1136/jmg.27.8.519
DP  - 1990 Aug 01
TA  - Journal of Medical Genetics
PG  - 519--522
VI  - 27
IP  - 8
4099  - http://jmg.bmj.com/content/27/8/519.short
4100  - http://jmg.bmj.com/content/27/8/519.full
SO  - J Med Genet1990 Aug 01; 27
AB  - Palmoplantar keratoderma (PPK) is a heterogeneous group of disorders. Epidermolytic PPK is a well delineated autosomal dominant entity, but no recessive form is known. Here we report two sons of phenotypically normal, consanguineous, Arab parents with features suggestive of PPK. They presented with patchy eczematous skin lesions followed by PPK and raised serum levels of IgE. Skin biopsy from the keratotic lesions showed the features of epidermolytic hyperkeratosis. Autosomal recessive inheritance is suggested and the differential diagnosis is discussed.