PT - JOURNAL ARTICLE AU - Colombo, B AU - Felicetti, L TI - Admission of Hb S heterozygotes to a general hospital is relatively reduced in malarial areas. AID - 10.1136/jmg.22.4.291 DP - 1985 Aug 01 TA - Journal of Medical Genetics PG - 291--292 VI - 22 IP - 4 4099 - http://jmg.bmj.com/content/22/4/291.short 4100 - http://jmg.bmj.com/content/22/4/291.full SO - J Med Genet1985 Aug 01; 22 AB - A comparison between the frequency of Hb S heterozygotes in blood donors, outpatients, and inpatients of a general hospital carried out at the Maputo Central Hospital, Mozambique, where Plasmodium falciparum malaria is endemic, showed a statistically significant lower percentage of Hb S heterozygotes in the inpatient group. Evidence is thus provided that the protection given by Hb S to heterozygotes concerns not only malarial infection itself, but probably a wide spectrum of diseases to which persons who have a special resistance to P falciparum infection are less prone.