PT - JOURNAL ARTICLE AU - Huson, S M AU - Meredith, A L AU - Sarfarazi, M AU - Shaw, D J AU - Compston, D A AU - Harper, P S TI - Linkage analysis of peripheral neurofibromatosis (Von Recklinghausen disease) and chromosome 19 markers linked to myotonic dystrophy. AID - 10.1136/jmg.23.1.55 DP - 1986 Feb 01 TA - Journal of Medical Genetics PG - 55--57 VI - 23 IP - 1 4099 - http://jmg.bmj.com/content/23/1/55.short 4100 - http://jmg.bmj.com/content/23/1/55.full SO - J Med Genet1986 Feb 01; 23 AB - Three chromosome 19 markers known to be linked to myotonic dystrophy have been studied in nine families with peripheral neurofibromatosis (Von Recklinghausen's disease). Clear evidence against linkage has been found for all three markers, excluding the peripheral neurofibromatosis gene from the myotonic dystrophy region of chromosome 19. Previous reports of co-inheritance of the two disorders in families cannot therefore be explained on the basis of close genetic linkage between the loci.