PT  - JOURNAL ARTICLE
AU  - D J Shaw
TI  - A new strategy for mapping the human genome.
AID  - 10.1136/jmg.23.5.421
DP  - 1986 Oct 01
TA  - Journal of Medical Genetics
PG  - 421--424
VI  - 23
IP  - 5
4099  - http://jmg.bmj.com/content/23/5/421.short
4100  - http://jmg.bmj.com/content/23/5/421.full
SO  - J Med Genet1986 Oct 01; 23
AB  - Recent advances in agarose gel electrophoresis of large DNA fragments raise the possibility of an entirely new approach to mapping mammalian genomes. In this article is discussed the potential of this technology for tackling problems such as construction of linkage maps, identifying chromosome translocation breakpoints, and moving from linked markers to genes causing diseases such as the muscular dystrophies and Huntington's chorea.