RT Journal Article
SR Electronic
T1 A new epsilon globin HincII variant fragment length in a South African Negroid family.
JF Journal of Medical Genetics
JO J Med Genet
FD BMJ Publishing Group Ltd
SP 145
OP 150
DO 10.1136/jmg.23.2.145
VO 23
IS 2
A1 Ramsay, M
A1 Thomson, J A
A1 Jenkins, T
YR 1986
UL http://jmg.bmj.com/content/23/2/145.abstract
AB A new HincII epsilon globin variant is reported in a South African Negroid family. The usual HincII epsilon globin fragment lengths are 8.0 and 3.7 kb and the variant described here is 14.0 kb in length. The 14.0 kb fragment was generated by a site alteration removing the 3' HincII site on a chromosome that already lacked the 5' HincII site. It appears that there are differences among races with regard to the frequencies of the 8.0 and 3.7 kb alleles. The 3.7 kb allele is the more common form in Caucasoids whereas the 8.0 kb allele occurs in the majority of Negroid and Khoisan subjects.