RT Journal Article
SR Electronic
T1 Monozygotic twins discordant for rubinstein-taybi syndrome.
JF Journal of Medical Genetics
JO J Med Genet
FD BMJ Publishing Group Ltd
SP 312
OP 314
DO 10.1136/jmg.18.4.312
VO 18
IS 4
A1 T Kajii
A1 K Hagiwara
A1 M Tsukahara
A1 H Nakajima
A1 Y Fukuda
YR 1981
UL http://jmg.bmj.com/content/18/4/312.abstract
AB A pair of male monozygotic twins discordant for Rubinstein-Taybi syndrome is reported. Monozygosity of the twins was established using blood grouping, typing of serum proteins, isozymes, HLA, and chromosomal heteromorphisms. The twins are the first twin pair discordant for the syndrome in which monozygosity has been firmly established. The pathogenesis of the syndrome is discussed in relation to the occurrence of both discordant and concordant monozygotic twins.