PT - JOURNAL ARTICLE AU - A C Berry AU - E M Belton AU - C Chantler TI - Monozygotic twins discordant for Wiedemann-Beckwith syndrome and the implications for genetic counselling. AID - 10.1136/jmg.17.2.136 DP - 1980 Apr 01 TA - Journal of Medical Genetics PG - 136--138 VI - 17 IP - 2 4099 - http://jmg.bmj.com/content/17/2/136.short 4100 - http://jmg.bmj.com/content/17/2/136.full SO - J Med Genet1980 Apr 01; 17 AB - A pair of monozygous twins discordant for Wiedemann-Beckwith syndrome is described and published reports reviewed to establish the mode of inheritance. Single gene control seems unlikely and it is proposed that the condition arises from the interaction of "at risk" genes in the fetus and metabolic factors in the mother, which suggests multifactorial control.