RT Journal Article SR Electronic T1 Down's syndrome in twins of unlike sex. JF Journal of Medical Genetics JO J Med Genet FD BMJ Publishing Group Ltd SP 94 OP 96 DO 10.1136/jmg.20.2.94 VO 20 IS 2 A1 A Avni A1 J Amir A1 E Wilunsky A1 M B Katznelson A1 S H Reisner YR 1983 UL http://jmg.bmj.com/content/20/2/94.abstract AB The occurrence of Down's syndrome in both dizygotic twins appears to be very rare. A case of twins of unlike sex is reported, in which chromosomal analysis showed trisomy 21 in both of them, while the parental karyotypes were normal. This is the third reported case of such a constellation, and the second one in which infant and parental chromosomal analysis was done.