TY - JOUR T1 - X;15 translocation in a retarded girl: X inactivation pattern and attempt to localise the hexosaminidase A and other loci. JF - Journal of Medical Genetics JO - J Med Genet SP - 254 LP - 262 DO - 10.1136/jmg.16.4.254 VL - 16 IS - 4 AU - R Bernstein AU - B Dawson AU - R Kohl AU - T Jenkins Y1 - 1979/08/01 UR - http://jmg.bmj.com/content/16/4/254.abstract N2 - Cytogenetic studies on a retarded girl showed a complex S;15 translocation, karyotype 45,X,-15,+t(X15). The translocation X chromosome was non-randomly partially inactivated, the inactivation being mainly confined to the X segment and in some cells only to the X long arm. Gene marker studies failed to show anomalous segregation of the hexosaminidase A gene or any other gene markers tested. ER -