TY - JOUR T1 - Down's syndrome and deletion of short arms of a G chromosome. JF - Journal of Medical Genetics JO - J Med Genet SP - 147 LP - 150 DO - 10.1136/jmg.14.2.147 VL - 14 IS - 2 AU - G H Ballantyne AU - M I Parslow AU - A M Veale AU - D H Pullon Y1 - 1977/04/01 UR - http://jmg.bmj.com/content/14/2/147.abstract N2 - A woman in a family in which a G group chromosome (No. 21) with deleted short arms (21p-) is present has passed this chromosome to an intellectually deficient son, a normal son, and a daughter with Down's syndrome. Another daughter is chromosomally and phenotypically normal. As in other reports that focus on a concurrence of Gp- chromosomes and Down's anomaly, the possibility is considered that this chromosomal variant may predispose to developmental abnormalities or to non-disjunction, or both. ER -