RT Journal Article
SR Electronic
T1 Prenatal diagnosis and gonadal findings in X/XXX mosaicism.
JF Journal of Medical Genetics
JO J Med Genet
FD BMJ Publishing Group Ltd
SP 120
OP 123
DO 10.1136/jmg.14.2.120
VO 14
IS 2
A1 G Kohn
A1 M M Cohen
A1 Y Beyth
A1 A Ornoy
YR 1977
UL http://jmg.bmj.com/content/14/2/120.abstract
AB Prenatal diagnosis of a case of X/XXX mosaicism is presented. In spite of the fact that over 50% of the cells cultured from both ovaries were trisomic for the X chromosome, fetal öocytes were rarely found. This case illustrates that the presence of a triple-X cell line, even in a relatively high percentage of ovarian cells, does not necessarily protect the ovary from 'aöogenesis'. This observation might prove useful in the counselling of future cases involving the prenatal detection of sex chromosome mosaicism.