RT Journal Article SR Electronic T1 Multiple congenital defects associated with trisomy for the short arm of chromosome 4 JF Journal of Medical Genetics JO J Med Genet FD BMJ Publishing Group Ltd SP 291 OP 295 DO 10.1136/jmg.11.3.291 VO 11 IS 3 A1 Owen, Lynne A1 Martin, Barbara A1 Blank, C. E. A1 Harris, F. YR 1974 UL http://jmg.bmj.com/content/11/3/291.abstract AB The clinical and cytogenetic findings of a female infant with multiple congenital anomalies and trisomy for the short arm of chromosome 4(46,XX,21p+) are described. The abnormal chromosome was inherited from the father who had a balanced translocation between the short arm of chromosome 4 and the short arm of chromosome 21. Clinical features are compared with those of one definite and one probable previously described case of trisomy for the short arm of chromosome 4. It is suggested that a clinical syndrome associated with +4p eventually may be identified.