PT  - JOURNAL ARTICLE
AU  - P A Stanway
AU  - I M Samloff
AU  - C J Brace
AU  - J H Renwick
TI  - Predisposition to spina bifida: Search for a relation to maternal gastric acid secretion.
AID  - 10.1136/jmg.14.5.332
DP  - 1977 Oct 01
TA  - Journal of Medical Genetics
PG  - 332--334
VI  - 14
IP  - 5
4099  - http://jmg.bmj.com/content/14/5/332.short
4100  - http://jmg.bmj.com/content/14/5/332.full
SO  - J Med Genet1977 Oct 01; 14
AB  - The peak acid output of the stomach in a group of 71 mothers of spina bifida children and in 71 matched controls was estimated indirectly by the serum level of group I pepsinogens. The mean levels did not differ significantly, suggesting that the conjectured teratogen is not specially acid-labile. The variance was significantly higher in index subjects than in controls, but the interpretation of this finding is not clear.