RT Journal Article
SR Electronic
T1 Dicentric Y chromosome in mixed gonadal dysgenesis.
JF Journal of Medical Genetics
JO J Med Genet
FD BMJ Publishing Group Ltd
SP 210
OP 212
DO 10.1136/jmg.12.2.210
VO 12
IS 2
A1 A Hayek
A1 E Yunis
YR 1975
UL http://jmg.bmj.com/content/12/2/210.abstract
AB A 15-year-old girl was investigated because of ambiguous genitalia. Her chromosome studies showed a 45, X/45, Xdic(Yq) mosaicism. The identity of the dicentric Y chromosome was demonstrated by its typical fluorescent banding patterns. Histological evidence of mixed gonadal dysgenesis with intragonadal tumour was observed, confirming the occurrence of gonadoblastoma associated with mosaicism in which at least one cell bears a Y chromosome.