PT - JOURNAL ARTICLE AU - A Hayek AU - E Yunis TI - Dicentric Y chromosome in mixed gonadal dysgenesis. AID - 10.1136/jmg.12.2.210 DP - 1975 Jun 01 TA - Journal of Medical Genetics PG - 210--212 VI - 12 IP - 2 4099 - http://jmg.bmj.com/content/12/2/210.short 4100 - http://jmg.bmj.com/content/12/2/210.full SO - J Med Genet1975 Jun 01; 12 AB - A 15-year-old girl was investigated because of ambiguous genitalia. Her chromosome studies showed a 45, X/45, Xdic(Yq) mosaicism. The identity of the dicentric Y chromosome was demonstrated by its typical fluorescent banding patterns. Histological evidence of mixed gonadal dysgenesis with intragonadal tumour was observed, confirming the occurrence of gonadoblastoma associated with mosaicism in which at least one cell bears a Y chromosome.