TY - JOUR T1 - A family study of coeliac disease. JF - Journal of Medical Genetics JO - J Med Genet SP - 79 LP - 82 DO - 10.1136/jmg.12.1.79 VL - 12 IS - 1 AU - T J David AU - A B Ajdukiewicz Y1 - 1975/03/01 UR - http://jmg.bmj.com/content/12/1/79.abstract N2 - Thirteen of 141 cases (9 percent) of overt, biopsy proven coeliac disease had a definitely affected relative. The pattern of inheritance in these families is compatible with an incompletely penetrant autosomal dominant gene. There was a female preponderance in the adults and the sporadic cases, but not in the children or the familial cases. The series included a pair of concordant and probably monozygotic twins. The authors believe that coeliac disease, as defined at present, is a heterogeneous condition. ER -