PT  - JOURNAL ARTICLE
AU  - P J Garry
AU  - A A Dietz
AU  - T Lubrano
AU  - P C Ford
AU  - K James
AU  - H M Rubinstein
TI  - New allele at cholinesterase locus 1.
AID  - 10.1136/jmg.13.1.38
DP  - 1976 Feb 01
TA  - Journal of Medical Genetics
PG  - 38--42
VI  - 13
IP  - 1
4099  - http://jmg.bmj.com/content/13/1/38.short
4100  - http://jmg.bmj.com/content/13/1/38.full
SO  - J Med Genet1976 Feb 01; 13
AB  - A family (H-J pedigree) segregating for the A and F alleles at cholinesterase locus 1 is described. Apparent anomalous results led to the recognition of a new allele (E1j) also segregating in the family. The data are consistent with the hypothesis that the the E1j causes reduction of 'usual' (E1u) molecules by about 66%. Whether this is because of retarded synthesis or accelerated degradation of serum cholinesterase remains to be determined.