RT Journal Article
SR Electronic
T1 G gamma delta beta thalassaemia and g gamma HPFH (Hb Kenya type): comparison of 2 new cases.
JF Journal of Medical Genetics
JO J Med Genet
FD BMJ Publishing Group Ltd
SP 237
OP 244
DO 10.1136/jmg.14.4.237
VO 14
IS 4
A1 W G Wood
A1 J B Clegg
A1 D J Weatherall
A1 O H Gyde
A1 D A Obeid
A1 M J Tarlow
A1 M J Brown
A1 S Hewitt
YR 1977
UL http://jmg.bmj.com/content/14/4/237.abstract
AB Two new cases of G gamma delta beta thalassaemia and G gamma HPFH (Hb Kenya type) have been characterised in detail and compared with regard to haematological data, globin chains biosynthesis, and intracellular distribution of Hb F. The similarities and differences between these two conditions are discussed in relation to the possible underlying defects at the molecular level and to the control of the gamma delta beta gene complex in general.