eLetters

22 e-Letters

published between 2009 and 2012

  • Change in stage distribution observed with annual screening for ovarian cancer in BRCA carriers
    Ranjit Manchanda

    Dear Sirs,

    We read with great interest the paper by Evans et al1 published online in your journal. The authors should be commended for having collected data from different sources to present a substantial series to try and draw some inferences. However their inferences from these data are questionable and they have failed to recognise that their data suggest a change in stage distribution as a result of screenin...

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  • Refining the critical region of the novel 19q13.11 microdeletion syndrome to 750 Kb.
    Bert B.A. De Vries

    With great interest we read the article of Malan et al., who reported on a novel clinically recognizable 19q13.11 microdeletion syndrome.1 Here we report on a fifth patient with an interstitial deletion overlapping the 19q13.11 region and compare our findings with those described by Malan et al. The proband was born after 37 weeks of gestation as one of dizygotic twins with a birth weight of 1620 g (-3.5 SD). His twin sist...

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