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SPINK1 mutations predispose to chronic pancreatitis
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There is a high prevalence of serine protease inhibitor Kazal type 1 (SPINK1) mutations, not only in chronic idiopathic, but also alcoholic pancreatitis, with around one in eight patients affected, finds Dutch research. The findings are based on mutational analysis of 115 adult patients with alcoholic (n=72), hereditary …