You are here

Article Text

Article menu
Download PDFPDF
Research Article
Prenatal diagnosis of thalassaemia major resulting from Lepore/ beta-thalassaemia genotype.
  1. M Furbetta,
  2. A Angius,
  3. A M Falchi,
  4. T Tuveri,
  5. Tannoia,
  6. A P Pertosa,
  7. A Cao

    Abstract

    Antenatal diagnosis was carried out in a pregnancy at risk for beta-thalassaemia major/intermedia, resulting from the Lepore/ beta-thalassaemia genotype, by globin chain synthesis analysis on fetal blood obtained by placentocentesis at 19 weeks' gestation. As there was no radioactive incorporation in the beta-region, the fetus was considered to be a Lepore/ beta-thalassaemia genetic compound and aborted on parental request. After abortion, cord blood analysis confirmed the absence of beta-chain radioactivity.

    https://doi.org/10.1136/jmg.18.6.476

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.