Diagnostic yield of chromosomal microarray and trio whole exome sequencing in cryptogenic cerebral palsy

Michal Yechieli; Suleyman Gulsuner; Hilla Ben-Pazi; Aviva Fattal; Adi Aran; Alla Kuzminsky; Liora Sagi; Dafna Guttman; Nira Schneebaum Sender; Varda Gross-Tsur; Tehila Klopstock; Tom Walsh; Paul Renbaum; Sharon Zeligson; Lilach Shemer Meiri; Dorit Lev; Dorit Shmueli; Luba Blumkin; Amnon Lahad; Mary-Claire King; Ephrat Lahad Levy; Reeval Segel

doi:10.1136/jmedgenet-2021-107884

Article info

Neurogenetics

Original research

Diagnostic yield of chromosomal microarray and trio whole exome sequencing in cryptogenic cerebral palsy

Authors

Michal Yechieli Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel PubMed articles Google scholar articles
Suleyman Gulsuner Department of Medicine and Department of Genome Sciences, University of Washington, Seattle, Washington, USA PubMed articles Google scholar articles
Hilla Ben-Pazi Pediatric Neurology, Shaare Zedek Medical Center, Jerusalem, IsraelFaculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel PubMed articles Google scholar articles
Aviva Fattal Pediatric Neurology Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel PubMed articles Google scholar articles
Adi Aran Pediatric Neurology, Shaare Zedek Medical Center, Jerusalem, IsraelFaculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel PubMed articles Google scholar articles
Alla Kuzminsky Pediatric Neurology Institute, Schneider Children's Medical Center of Israel, Petah Tikva, Israel PubMed articles Google scholar articles
Liora Sagi Pediatric Neurology Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel PubMed articles Google scholar articles
Dafna Guttman Pediatric Rehabilitation Department, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel PubMed articles Google scholar articles
Nira Schneebaum Sender Pediatric Neurology Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel PubMed articles Google scholar articles
Varda Gross-Tsur Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, IsraelPediatric Neurology Unit, Shaare Zedek Medical Center, Jerusalem, Israel PubMed articles Google scholar articles
Tehila Klopstock Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, IsraelMedical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel PubMed articles Google scholar articles
Tom Walsh Department of Medicine and Department of Genome Sciences, University of Washington, Seattle, Washington, USA PubMed articles Google scholar articles
Paul Renbaum Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel PubMed articles Google scholar articles
Sharon Zeligson Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel PubMed articles Google scholar articles
Lilach Shemer Meiri Pediatric Neurology unit, Carmel Hospital, Haifa, Israel PubMed articles Google scholar articles
Dorit Lev Sackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelInstitute of Medical Genetics, Edith Wolfson Medical Center, Holon, Israel PubMed articles Google scholar articles
Dorit Shmueli Child Development Services, Clalit Health Services, Tel Aviv, Israel PubMed articles Google scholar articles
Luba Blumkin Sackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelPediatric Neurology, Edith Wolfson Hospital, Holon, Israel PubMed articles Google scholar articles
Amnon Lahad Braun School of Public Health, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, IsraelDepartment of Family Medicine, Clalit Health Services, Jerusalem, Israel PubMed articles Google scholar articles
Mary-Claire King Department of Medicine and Department of Genome Sciences, University of Washington, Seattle, Washington, USA PubMed articles Google scholar articles
Ephrat Lahad Levy Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, IsraelMedical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel PubMed articles Google scholar articles
Reeval Segel Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, IsraelMedical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel PubMed articles Google scholar articles

Correspondence to Dr Reeval Segel, Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Jerusalem, Israel; reevals{at}szmc.org.il

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Citation

Yechieli M, Gulsuner S, Ben-Pazi H, et al

Diagnostic yield of chromosomal microarray and trio whole exome sequencing in cryptogenic cerebral palsy

Journal of Medical Genetics Published Online First: 28 July 2021. doi: 10.1136/jmedgenet-2021-107884

Publication history

Received April 4, 2021
Accepted July 14, 2021
First published July 28, 2021.

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