Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study

Andreas Beyerlein; Ezio Bonifacio; Kendra Vehik; Markus Hippich; Christiane Winkler; Brigitte I Frohnert; Andrea K Steck; William A Hagopian; Jeffrey P Krischer; Åke Lernmark; Marian J Rewers; Jin-Xiong She; Jorma Toppari; Beena Akolkar; Stephen S Rich; Anette-G Ziegler

doi:10.1136/jmedgenet-2018-105532

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Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study

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Andreas Beyerlein Institute of Diabetes Research, Helmholtz Zentrum München, and Forschergruppe Diabetes, Technical University of Munich, at Klinikum rechts der Isar, Munich-Neuherberg, Germany PubMed articles Google scholar articles
Ezio Bonifacio DFG Center for Regenerative Therapies Dresden, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany Forschergruppe Diabetes eV at Helmholtz Zentrum München, Munich-Neuherberg, Germany PubMed articles Google scholar articles
Kendra Vehik Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA PubMed articles Google scholar articles
Markus Hippich Institute of Diabetes Research, Helmholtz Zentrum München, and Forschergruppe Diabetes, Technical University of Munich, at Klinikum rechts der Isar, Munich-Neuherberg, Germany PubMed articles Google scholar articles
Christiane Winkler Institute of Diabetes Research, Helmholtz Zentrum München, and Forschergruppe Diabetes, Technical University of Munich, at Klinikum rechts der Isar, Munich-Neuherberg, Germany Forschergruppe Diabetes eV at Helmholtz Zentrum München, Munich-Neuherberg, Germany PubMed articles Google scholar articles
Brigitte I Frohnert Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, Colorado, USA PubMed articles Google scholar articles
Andrea K Steck Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, Colorado, USA PubMed articles Google scholar articles
William A Hagopian Pacific Northwest Diabetes Research Institute, Seattle, Washington, USA PubMed articles Google scholar articles
Jeffrey P Krischer Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA PubMed articles Google scholar articles
Åke Lernmark Department of Clinical Sciences, Lund University/CRC, Skåne University Hospital SUS, Malmo, Sweden PubMed articles Google scholar articles
Marian J Rewers Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, Colorado, USA PubMed articles Google scholar articles
Jin-Xiong She Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia, USA PubMed articles Google scholar articles
Jorma Toppari Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, Turku University Hospital, Turku, Finland Department of Physiology, University of Turku, Turku, Finland PubMed articles Google scholar articles
Beena Akolkar National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA PubMed articles Google scholar articles
Stephen S Rich Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA PubMed articles Google scholar articles
Anette-G Ziegler Institute of Diabetes Research, Helmholtz Zentrum München, and Forschergruppe Diabetes, Technical University of Munich, at Klinikum rechts der Isar, Munich-Neuherberg, Germany Forschergruppe Diabetes eV at Helmholtz Zentrum München, Munich-Neuherberg, Germany PubMed articles Google scholar articles
the TEDDY Study Group
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Correspondence to Dr Anette-G Ziegler, Institute of Diabetes Research, Helmholtz Zentrum München, Munich-Neuherberg, 85764, Germany; anette-g.ziegler{at}helmholtz-muenchen.de

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Citation

Beyerlein A, Bonifacio E, Vehik K the TEDDY Study Group, et al

Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study

Journal of Medical Genetics 2019;56:602-605.

Publication history

Received June 12, 2018
Revised August 16, 2018
Accepted September 13, 2018
First published October 4, 2018.

Online issue publication

August 21, 2019

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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