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  • Haemophagocytic lymphohistiocytosis complicating pembrolizumab treatment for metastatic breast cancer in a patient with the PRF1A91V gene polymorphism

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Immunogenetics
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Haemophagocytic lymphohistiocytosis complicating pembrolizumab treatment for metastatic breast cancer in a patient with the PRF1A91V gene polymorphism

Authors

  • Hanny Al-Samkari Center for Hematology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts, USA Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Gregory D Snyder Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Sarah Nikiforow Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Sara M Tolaney Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Rachel A Freedman Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Julie-Aurore Losman Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA Division of Hematology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Julie-Aurore Losman, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Julieaurore_Losman{at}dfci.harvard.edu
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Citation

Al-Samkari H, Snyder GD, Nikiforow S, et al
Haemophagocytic lymphohistiocytosis complicating pembrolizumab treatment for metastatic breast cancer in a patient with the PRF1A91V gene polymorphism
Journal of Medical Genetics 2019;56:39-42.

Publication history

  • Received May 14, 2018
  • Revised June 12, 2018
  • Accepted September 18, 2018
  • First published October 4, 2018.
Online issue publication 
December 13, 2018

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© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.