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Cancer genetics
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TP53 c.455C>T p.(Pro152Leu) pathogenic variant is a lower risk allele with attenuated risks of breast cancer and sarcoma

Authors

  • D Gareth Evans Division of Evolution, Infection and Genomics, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK PubMed articlesGoogle scholar articles
  • Elaine F Harkness Division of Informatics, Imaging and Data Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK PubMed articlesGoogle scholar articles
  • Emma R Woodward Division of Evolution, Infection and Genomics, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK PubMed articlesGoogle scholar articles
  1. Correspondence to D Gareth Evans, Division of Evolution, Infection and Genomics, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; gareth.evans{at}mft.nhs.uk
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Citation

Evans DG, Harkness EF, Woodward ER
TP53 c.455C>T p.(Pro152Leu) pathogenic variant is a lower risk allele with attenuated risks of breast cancer and sarcoma
Journal of Medical Genetics 2023;60:1057-1060.

Publication history

  • Received December 30, 2022
  • Accepted March 10, 2023
  • First published April 19, 2023.
Online issue publication 
October 24, 2023

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© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.