Table of contents

Cancer genetics

• Original research:

  Oncologist-led BRCA counselling improves access to cancer genetic testing in middle-income Asian country, with no significant impact on psychosocial outcomes

  (1 February, 2021)

  Sook-Yee Yoon, Siu Wan Wong, Joanna Lim, Syuhada Ahmad, Shivaani Mariapun, Heamanthaa Padmanabhan, Nur Tiara Hassan, Shao Yan Lau, Gaik-Siew Ch'ng, Muzhirah Haniffa, Winnie P Ong, Kavitha Rethanavelu, Lip Hen Moey, Wee Teik Keng, Jamil Omar, Mohd Norazam Mohd Abas, Chee Meng Yong, Vickneswaren Ramasamy, Mohd Rushdan Md Noor, Ismail Aliyas, Michael C K Lim, Anuradha Suberamaniam, Noor Azmi Mat Adenan, Zatul Akmar Ahmad, Gwo Fuang Ho, Rozita Abdul Malik, Suguna Subramaniam, Boom Ping Khoo, Arivendran Raja, Yeung Sing Chin, Wee Wee Sim, Beng Hock Teh, Swee Kiong Kho, Eunice S E Ong, Pei Jye Voon, Ghazali Ismail, Chui Ling Lee, Badrul Zaman Abdullah, Kwong Sheng Loo, Chun Sen Lim, Saw Joo Lee, Keng Joo Lim Lim, Mohamad Nasir Shafiee, Fuad Ismail, Zarina Abdul Latiff, Mohd Pazudin Ismail, Mohamad Faiz Mohamed Jamli, Suresh Kumarasamy, Kin Wah Leong, John Low, Mastura Md Yusof, Ahmad Muzamir Ahmad Mustafa, Nor Huda Mat Ali, Mary Makanjang, Shahila Tayib, Nellie Cheah, Boon Kiong Lim, Chee Kin Fong, Yoke Ching Foo, Matin Mellor Abdullah, Teck Sin Tan, Doris S Y Chow, Kean Fatt Ho, Rakesh Raman, Ahmad Radzi, Azura Deniel, Daren C Y Teoh, Soo Fan Ang, Joseph K Joseph, Paul Hock Oon Ng, Lye-Mun Tho, Azura Rozila Ahmad, Ileena Muin, Eveline Bleiker, Angela George, Meow-Keong Thong, Yin Ling Woo, Soo Hwang Teo
• Original research:

  Comprehensive evaluation of BRCA1/2 variant interpretation ability among laboratories in China

  (4 January, 2021)

  Kang Shao, Ruixia Wang, Shoufang Qu, Wenxin Zhang, Ting Yu, Boyang Cao, Pingping Dai, Anna Zhu, Jianguang Zhang, Juan Wang, Lusheng Wang, Shida Zhu, Kui Wu, Xuexi Yang, Xiaoyan Chang, Fang Chen, Jie Huang
• Original research: Pregnancy outcomes in women with neurofibromatosis 1: a Danish population-based cohort study (25 January, 2021)

  Line Kenborg, Cristina Boschini, Pernille E Bidstrup, Susanne O Dalton, Karoline Doser, Thomas T Nielsen, Anja Krøyer, Christoffer Johansen, Kirsten Frederiksen, Sven Asger Sørensen, Hanne Hove, John R Østergaard, John J Mulvihill, Jeanette F Winther
• Short report: Calibration of polygenic risk scores is required prior to clinical implementation: results of three common cancers in UKB (21 December, 2020)

  Jun Wei, Zhuqing Shi, Rong Na, W Kyle Resurreccion, Chi-Hsiung Wang, David Duggan, S Lilly Zheng, Peter J Hulick, Brian T Helfand, Jianfeng Xu
• Short report:

  Sensitivity and specificity of loss of heterozygosity analysis for the classification of rare germline variants in BRCA1/2: results of the observational AGO-TR1 study (NCT02222883)

  (3 December, 2020)

  Jan Hauke, Philipp Harter, Corinna Ernst, Alexander Burges, Sandra Schmidt, Alexander Reuss, Julika Borde, Nikolaus De Gregorio, Dimo Dietrich, Ahmed El-Balat, Mohamad Kayali, Heidrun Gevensleben, Felix Hilpert, Janine Altmüller, André Heimbach, Werner Meier, Birgid Schoemig-Markiefka, Holger Thiele, Rainer Kimmig, Peter Nürnberg, Karin Kast, Lisa Richters, Jalid Sehouli, Rita K Schmutzler, Eric Hahnen