Table of contents

Cancer genetics

• Original research: High likelihood of actionable pathogenic variant detection in breast cancer genes in women with very early onset breast cancer (23 March, 2021)

  D Gareth Evans, Elke Maria van Veen, Helen J Byers, Sarah J Evans, George J Burghel, Emma Roisin Woodward, Elaine F Harkness, Diana M Eccles, Stephanie L Greville-Haygate, Jamie M Ellingford, Naomi L Bowers, Marta Pereira, Andrew J Wallace, Sasha J Howell, Anthony Howell, Fiona Lalloo, William G Newman, Miriam Jane Smith
• Original research:

  Surgical decision making in premenopausal BRCA carriers considering risk-reducing early salpingectomy or salpingo-oophorectomy: a qualitative study

  (10 February, 2021)

  Faiza Gaba, Shivam Goyal, Dalya Marks, Dhivya Chandrasekaran, Olivia Evans, Sadiyah Robbani, Charlotte Tyson, Rosa Legood, Ertan Saridogan, W Glenn McCluggage, Helen Hanson, Naveena Singh, D Gareth Evans, Usha Menon, Ranjit Manchanda
• Original research:

  Uptake and efficacy of bilateral risk reducing surgery in unaffected female BRCA1 and BRCA2 carriers

  (10 February, 2021)

  Ruta Marcinkute, Emma Roisin Woodward, Ashu Gandhi, Sacha Howell, Emma J Crosbie, Julie Wissely, James Harvey, Lindsay Highton, John Murphy, Cathrine Holland, Richard Edmondson, Richard Clayton, Lester Barr, Elaine F Harkness, Anthony Howell, Fiona Lalloo, D Gareth Evans
• Short report: A complex DICER1 syndrome phenotype associated with a germline pathogenic variant affecting the RNase IIIa domain of DICER1 (18 November, 2020)

  Emeli Pontén, Sofia Frisk, Fulya Taylan, Raquel Vaz, Sandra Wessman, Leanne de Kock, Niklas Pal, William D Foulkes, Kristina Lagerstedt-Robinson, Ann Nordgren