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A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia

Authors

  • Ho Tsoi Faculty of Science, Laboratory of Drosophila Research, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong Faculty of Science, Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Allen C S Yu Faculty of Science, Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Zhefan S Chen Faculty of Science, Laboratory of Drosophila Research, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong Faculty of Science, Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Nelson K N Ng Faculty of Science, Laboratory of Drosophila Research, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong Faculty of Science, Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Anne Y Y Chan Faculty of Medicine, Division of Neurology, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Liz Y P Yuen Faculty of Medicine, Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Jill M Abrigo Faculty of Medicine, Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Suk Ying Tsang Faculty of Science, Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong Partner State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Stephen K W Tsui Faculty of Medicine, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Tony M F Tong Clinical Genetic Service, Department of Health, The Government of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Ivan F M Lo Clinical Genetic Service, Department of Health, The Government of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Stephen T S Lam Clinical Genetic Service, Department of Health, The Government of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Vincent C T Mok Faculty of Medicine, Division of Neurology, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Lawrence K S Wong Faculty of Medicine, Division of Neurology, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Jacky C K Ngo Faculty of Science, Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Kwok-Fai Lau Faculty of Science, Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • Ting-Fung Chan Faculty of Science, Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong Partner State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  • H Y Edwin Chan Faculty of Science, Laboratory of Drosophila Research, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong Faculty of Science, Biochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong PubMed articlesGoogle scholar articles
  1. Correspondence to Dr H Y Edwin Chan, School of Life Sciences, Room 509B, Mong Man Wai Building, The Chinese University of Hong Kong, Hong Kong, Hong Kong; hyechan{at}cuhk.edu.hk  Dr Ting-Fung Chan, School of Life Sciences, Room 177, Science Centre South Block, The Chinese University of Hong Kong, Hong Kong; tf.chan@cuhk.edu.hk
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Citation

Tsoi H, Yu ACS, Chen ZS, et al
A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia

Publication history

  • Received February 10, 2014
  • Revised June 9, 2014
  • Accepted July 5, 2014
  • First published July 25, 2014.
Online issue publication 
April 27, 2016

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