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Complex traits
Original article
HLA alleles as biomarkers of high-titre neutralising antibodies to interferon-β therapy in multiple sclerosis

Authors

  • Concepción Núñez Immunology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain PubMed articlesGoogle scholar articles
  • Mª Carmen Cénit Immunology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain PubMed articlesGoogle scholar articles
  • Roberto Alvarez-Lafuente Multiple Sclerosis Unit, Neurology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain PubMed articlesGoogle scholar articles
  • Jordi Río Department of Neurology-Neuroimmunology, Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron University Hospital, Barcelona, Spain PubMed articlesGoogle scholar articles
  • Miguel Fernández-Arquero Immunology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain PubMed articlesGoogle scholar articles
  • Rafael Arroyo Multiple Sclerosis Unit, Neurology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain PubMed articlesGoogle scholar articles
  • Xavier Montalbán Department of Neurology-Neuroimmunology, Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron University Hospital, Barcelona, Spain PubMed articlesGoogle scholar articles
  • Oscar Fernández Servicio de Neurología, Instituto de Neurociencias Clínicas, Hospital Regional Universitario, Málaga, Spain PubMed articlesGoogle scholar articles
  • Begoña Oliver-Martos Laboratorio de Investigación, Instituto de Neurociencias Clínicas, Hospital Regional Universitario, Málaga, Spain PubMed articlesGoogle scholar articles
  • Laura Leyva Laboratorio de Investigación, Instituto de Neurociencias Clínicas, Hospital Regional Universitario, Málaga, Spain PubMed articlesGoogle scholar articles
  • Manuel Comabella Department of Neurology-Neuroimmunology, Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron University Hospital, Barcelona, Spain PubMed articlesGoogle scholar articles
  • Elena Urcelay Immunology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Elena Urcelay, Immunology Department, Hospital Clínico San Carlos, IdISSC, Martin Lagos s/n, Madrid 28040, Spain; elena.urcelay{at}salud.madrid.org, eurcelay.hcsc{at}salud.madrid.org
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Citation

Núñez C, Cénit MC, Alvarez-Lafuente R, et al
HLA alleles as biomarkers of high-titre neutralising antibodies to interferon-β therapy in multiple sclerosis
Journal of Medical Genetics 2014;51:395-400.

Publication history

  • Received February 10, 2014
  • Accepted March 6, 2014
  • First published April 19, 2014.
Online issue publication 
April 27, 2016

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