You are here

Article info

Article menu
Download PDFPDF
Cancer genetics
Original article
Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC)

Authors

  • K Newton Department of General Surgery, Manchester Royal Infirmary, Central Manchester University Hospitals NHS Trust, Manchester, UK PubMed articlesGoogle scholar articles
  • N M Jorgensen Genomic Diagnostics Laboratory, Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Saint Mary's Hospital, Manchester, UK PubMed articlesGoogle scholar articles
  • A J Wallace Genomic Diagnostics Laboratory, Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Saint Mary's Hospital, Manchester, UK PubMed articlesGoogle scholar articles
  • D D Buchanan Cancer and Population Studies Group, Queensland Institute of Medical Research, Herston, Queensland, Australia Oncogenomics Group, Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • F Lalloo Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Saint Mary's Hospital, Manchester, UK PubMed articlesGoogle scholar articles
  • R F T McMahon Department of Histopathology, Manchester Royal Infirmary, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK Manchester Medical School, University of Manchester, Manchester, UK PubMed articlesGoogle scholar articles
  • J Hill Department of General Surgery, Manchester Royal Infirmary, Central Manchester University Hospitals NHS Trust, Manchester, UK PubMed articlesGoogle scholar articles
  • D G Evans Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Saint Mary's Hospital, Manchester, UK PubMed articlesGoogle scholar articles
  1. Correspondence to K Newton, Genomic Diagnostics Laboratory, Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Saint Mary's Hospital, Oxford Road, Manchester M13 9WL UK; Katynewton2012{at}doctors.org.uk
View Full Text

Citation

Newton K, Jorgensen NM, Wallace AJ, et al
Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC)
Journal of Medical Genetics 2014;51:789-796.

Publication history

  • Received May 27, 2014
  • Revised September 3, 2014
  • Accepted September 10, 2014
  • First published October 3, 2014.
Online issue publication 
April 27, 2016

Article Versions

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Copyright information

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions