Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer

M P Hitchins; R L Ward

doi:10.1136/jmg.2009.068122

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Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer

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	Abstract	Full	Pdf
Jun 2009	18	0	10
Jul 2009	135	0	96
Aug 2009	184	0	40
Sep 2009	62	0	54
Oct 2009	125	0	32
Nov 2009	40	9	46
Dec 2009	463	43	115
Jan 2010	165	45	144
Feb 2010	40	34	33
Mar 2010	43	25	34
Apr 2010	63	36	41
May 2010	27	52	50
Jun 2010	32	41	54
Jul 2010	27	38	38
Aug 2010	17	77	53
Sep 2010	56	106	37
Oct 2010	30	106	41
Nov 2010	30	44	41
Dec 2010	29	43	44
Jan 2011	34	112	58
Feb 2011	29	62	44
Mar 2011	47	69	49
Apr 2011	29	35	39
May 2011	34	61	48
Jun 2011	24	48	44
Jul 2011	41	40	36
Aug 2011	25	41	46
Sep 2011	18	29	29
Oct 2011	31	39	33
Nov 2011	31	26	30
Dec 2011	29	50	36
Jan 2012	27	53	34
Feb 2012	26	25	20
Mar 2012	26	54	24
Apr 2012	37	40	26
May 2012	19	44	25
Jun 2012	24	33	40
Jul 2012	33	46	42
Aug 2012	29	26	19
Sep 2012	31	26	28
Oct 2012	43	30	34
Nov 2012	36	30	28
Dec 2012	38	10	12
Jan 2013	59	38	14
Feb 2013	55	26	16
Mar 2013	39	24	15
Apr 2013	36	25	21
May 2013	40	22	13
Jun 2013	17	31	18
Jul 2013	40	14	11
Aug 2013	30	17	12
Sep 2013	16	24	14
Oct 2013	33	27	10
Nov 2013	20	16	17
Dec 2013	25	19	17
Jan 2014	25	16	18
Feb 2014	10	19	11
Mar 2014	20	12	43
Apr 2014	27	16	15
May 2014	37	16	16
Jun 2014	26	15	14
Jul 2014	15	11	8
Aug 2014	20	15	10
Sep 2014	24	25	22
Oct 2014	7	15	4
Nov 2014	9	6	8
Dec 2014	12	8	11
Jan 2015	13	12	11
Feb 2015	15	10	12
Mar 2015	15	11	6
Apr 2015	22	16	9
May 2015	8	14	15
Jun 2015	7	16	8
Jul 2015	6	6	5
Aug 2015	12	10	9
Sep 2015	18	21	7
Oct 2015	22	3	6
Nov 2015	19	20	16
Dec 2015	18	9	6
Jan 2016	17	21	11
Feb 2016	6	5	5
Mar 2016	22	8	13
Apr 2016	17	10	9
May 2016	15	9	13
Jun 2016	17	13	7
Jul 2016	15	12	5
Aug 2016	22	17	17
Sep 2016	28	9	8
Oct 2016	7	9	6
Nov 2016	14	11	8
Dec 2016	16	14	5
Jan 2017	12	8	5
Feb 2017	7	11	9
Mar 2017	7	15	8
Apr 2017	3	21	4
May 2017	1	25	15
Jun 2017	14	31	8
Jul 2017	19	16	6
Aug 2017	34	24	4
Sep 2017	32	26	9
Oct 2017	38	28	5
Nov 2017	33	27	2
Dec 2017	15	15	4
Jan 2018	27	15	2
Feb 2018	31	20	4
Mar 2018	40	32	14
Apr 2018	23	23	5
May 2018	31	29	6
Jun 2018	29	27	4
Jul 2018	24	22	6
Aug 2018	91	83	3
Sep 2018	146	142	6
Oct 2018	126	118	12
Nov 2018	146	143	15
Dec 2018	154	152	6
Jan 2019	133	130	9
Feb 2019	122	117	6
Mar 2019	53	53	18
Apr 2019	39	37	15
May 2019	33	31	11
Jun 2019	18	13	9
Jul 2019	18	17	12
Aug 2019	25	19	11
Sep 2019	32	32	10
Oct 2019	33	27	22
Nov 2019	18	12	5
Dec 2019	18	14	7
Jan 2020	31	31	10
Feb 2020	20	16	9
Mar 2020	20	20	10
Apr 2020	10	10	7
May 2020	25	23	10
Jun 2020	23	22	7
Jul 2020	37	35	11
Aug 2020	22	18	9
Sep 2020	38	24	18
Oct 2020	49	33	24
Nov 2020	64	43	12
Dec 2020	36	29	8
Jan 2021	21	21	7
Feb 2021	37	31	11
Mar 2021	41	32	29
Apr 2021	28	18	18
May 2021	45	41	27
Jun 2021	25	22	11
Jul 2021	17	17	10
Aug 2021	21	20	18
Sep 2021	13	13	14
Oct 2021	32	26	23
Nov 2021	33	27	35
Dec 2021	34	28	23
Jan 2022	36	26	18
Feb 2022	49	29	7
Mar 2022	53	36	18
Apr 2022	51	37	16
May 2022	64	44	23
Jun 2022	68	41	16
Jul 2022	36	28	10
Aug 2022	33	30	16
Sep 2022	47	36	27
Oct 2022	50	39	48
Nov 2022	64	44	11
Dec 2022	57	33	9
Jan 2023	75	47	32
Feb 2023	62	54	17
Mar 2023	71	51	18
Apr 2023	46	26	17
Total	6549	5227	3363

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