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GATA4 sequence variants in patients with congenital heart disease
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- Published on: 21 December 2007
- Published on: 21 December 2007We need a detailed Phenome in the PHENOMEnon of genetics and congenital heart diseaseDear EditorShow More
In their interesting manuscript, Tomita-Mitchell and colleagues present four novel GATA4 sequence variations as pathogenic substrates for congenital heart disease (CHD) in humans[1]. CHD are the most common birth defect and affect almost 1% of all newborns. Since surgical approaches have substantially improved over the last decades, the number of grown ups with CHD (GUCH) is growing continuously. This fact dema...
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