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The congenital myasthenic syndrome mutation RAPSN N88K derives from an ancient Indo-European founder

https://doi.org/10.1136/jmg.2004.021139

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    Footnotes

    • ↵* These authors contributed equally to this paper.

    • This work was supported by grants from the Deutsche Forschungsgemeinschaft (DFG) and the Deutsche Gesellschaft für Muskelkranke (DGM) to HL and AA, by grants from the Medical Research Council (UK) and the Muscular Dystrophy Campaign/Myasthenia Gravis Association of Great Britain to DB, and by grants from the Institut National de la Santé et de la Recherche Médicale (INSERM), the Assistance Publique-Hôpitaux de Paris (APHP), and the Association Française contre les Myopathies (AFM) to PR, BE, and DH. JSM receives a scholarship from the Boehringer Ingelheim Fonds. SKB receives a scholarship through the program for molecular medicine of the Ludwig-Maximilians-University, Munich.

    • Conflict of interest: none declared.