A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions

K J Griffin; L S Kirschner; L Matyakhina; S G Stergiopoulos; A Robinson-White; S M Lenherr; F D Weinberg; E S Claflin; D Batista; I Bourdeau; A Voutetakis; F Sandrini; E M Meoli; A J Bauer; Y S Cho-Chung; S R Bornstein; J A Carney; C A Stratakis

doi:10.1136/jmg.2004.028043

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Original article

A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions

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	Abstract	Full	Pdf
Dec 2004	490	89	31
Jan 2005	164	125	45
Feb 2005	51	72	17
Mar 2005	39	76	8
Apr 2005	9	35	9
May 2005	11	33	11
Jun 2005	13	36	9
Jul 2005	9	27	4
Aug 2005	7	25	3
Sep 2005	7	26	8
Oct 2005	17	26	4
Nov 2005	12	23	11
Dec 2005	12	22	15
Jan 2006	9	33	16
Feb 2006	7	24	16
Mar 2006	8	22	14
Apr 2006	4	15	8
May 2006	2	17	7
Jun 2006	6	24	7
Jul 2006	3	9	8
Aug 2006	5	8	5
Sep 2006	5	15	6
Oct 2006	8	8	5
Nov 2006	9	12	11
Dec 2006	4	15	7
Jan 2007	2	17	16
Feb 2007	4	8	4
Mar 2007	6	21	12
Apr 2007	8	5	3
May 2007	5	9	13
Jun 2007	13	7	4
Jul 2007	9	5	2
Aug 2007	3	6	4
Sep 2007	1	3	4
Oct 2007	9	6	4
Nov 2007	4	6	1
Dec 2007	7	6	3
Jan 2008	16	7	3
Feb 2008	5	7	5
Mar 2008	14	3	6
Apr 2008	11	5	6
May 2008	8	4	4
Jun 2008	6	4	1
Jul 2008	10	6	6
Aug 2008	10	7	7
Sep 2008	22	7	4
Oct 2008	7	2	0
Nov 2008	54	4	8
Dec 2008	1	3	1
Jan 2009	4	2	2
Feb 2009	8	0	1
Mar 2009	5	3	0
Apr 2009	9	1	3
May 2009	8	7	2
Jun 2009	6	2	2
Jul 2009	7	2	2
Aug 2009	9	2	2
Sep 2009	11	5	5
Oct 2009	20	4	3
Nov 2009	8	2	3
Dec 2009	31	0	8
Jan 2010	6	0	1
Feb 2010	6	1	0
Mar 2010	8	0	0
Apr 2010	7	9	5
May 2010	12	1	2
Jun 2010	5	1	3
Jul 2010	10	2	2
Aug 2010	37	20	2
Sep 2010	58	20	3
Oct 2010	46	21	5
Nov 2010	47	39	6
Dec 2010	40	18	3
Jan 2011	62	29	3
Feb 2011	48	23	0
Mar 2011	74	27	3
Apr 2011	27	21	2
May 2011	24	19	4
Jun 2011	15	12	2
Jul 2011	45	10	2
Aug 2011	22	4	1
Sep 2011	23	18	4
Oct 2011	31	11	0
Nov 2011	32	13	1
Dec 2011	15	71	5
Jan 2012	16	69	5
Feb 2012	15	89	5
Mar 2012	11	72	7
Apr 2012	11	52	4
May 2012	10	45	5
Jun 2012	13	28	7
Jul 2012	12	33	14
Aug 2012	13	31	8
Sep 2012	19	74	6
Oct 2012	11	72	5
Nov 2012	86	105	3
Dec 2012	55	45	2
Jan 2013	30	25	5
Feb 2013	16	11	8
Mar 2013	11	12	4
Apr 2013	35	9	3
May 2013	19	24	5
Jun 2013	7	4	1
Jul 2013	17	11	7
Aug 2013	10	15	1
Sep 2013	18	26	2
Oct 2013	19	46	3
Nov 2013	7	35	4
Dec 2013	13	59	2
Jan 2014	16	38	1
Feb 2014	11	42	6
Mar 2014	16	47	9
Apr 2014	14	63	11
May 2014	9	34	2
Jun 2014	12	37	8
Jul 2014	9	43	6
Aug 2014	11	44	2
Sep 2014	2	38	3
Oct 2014	10	29	3
Nov 2014	12	14	1
Dec 2014	15	9	2
Jan 2015	10	4	4
Feb 2015	6	1	3
Mar 2015	7	9	0
Apr 2015	5	10	4
May 2015	8	14	1
Jun 2015	2	6	0
Jul 2015	6	14	3
Aug 2015	8	287	1
Sep 2015	16	34	3
Oct 2015	5	9	4
Nov 2015	8	8	2
Dec 2015	19	20	9
Jan 2016	21	17	1
Feb 2016	20	5	1
Mar 2016	7	4	7
Apr 2016	13	6	2
May 2016	9	11	4
Jun 2016	15	5	0
Jul 2016	12	4	3
Aug 2016	11	7	0
Sep 2016	24	5	4
Oct 2016	12	6	2
Nov 2016	14	8	1
Dec 2016	7	7	4
Jan 2017	10	5	3
Feb 2017	1	5	0
Mar 2017	0	17	4
Apr 2017	3	14	0
May 2017	1	13	0
Jun 2017	8	19	1
Jul 2017	13	13	0
Aug 2017	11	11	1
Sep 2017	36	36	3
Oct 2017	26	24	6
Nov 2017	30	26	1
Dec 2017	16	14	3
Jan 2018	20	16	5
Feb 2018	38	36	2
Mar 2018	31	31	1
Apr 2018	36	34	1
May 2018	23	21	0
Jun 2018	23	21	3
Jul 2018	36	34	2
Aug 2018	9	9	1
Sep 2018	16	14	6
Oct 2018	46	46	3
Nov 2018	47	47	2
Dec 2018	71	71	5
Jan 2019	53	52	2
Feb 2019	43	41	5
Mar 2019	26	24	5
Apr 2019	3	3	4
May 2019	13	13	4
Jun 2019	3	3	5
Jul 2019	2	2	8
Aug 2019	4	4	4
Sep 2019	5	5	3
Oct 2019	15	12	3
Nov 2019	10	7	5
Dec 2019	17	17	3
Jan 2020	16	14	2
Feb 2020	3	3	2
Mar 2020	4	4	6
Apr 2020	10	8	6
May 2020	15	14	6
Jun 2020	9	7	3
Jul 2020	11	11	5
Aug 2020	3	3	6
Sep 2020	18	16	5
Oct 2020	26	21	10
Nov 2020	13	13	4
Dec 2020	7	7	3
Jan 2021	10	9	6
Feb 2021	9	9	2
Mar 2021	16	16	4
Apr 2021	10	10	3
May 2021	2	2	2
Jun 2021	5	5	2
Jul 2021	4	4	9
Aug 2021	5	7	9
Sep 2021	14	14	12
Oct 2021	14	14	18
Nov 2021	8	8	13
Dec 2021	12	12	2
Jan 2022	10	10	5
Feb 2022	11	10	6
Mar 2022	17	15	11
Apr 2022	17	11	8
May 2022	29	28	11
Jun 2022	26	26	5
Jul 2022	19	14	1
Aug 2022	29	25	3
Sep 2022	28	28	24
Oct 2022	27	27	8
Nov 2022	9	7	4
Dec 2022	17	11	2
Jan 2023	29	25	5
Feb 2023	28	28	5
Mar 2023	7	5	5
Apr 2023	13	11	10
May 2023	9	6	5
Jun 2023	9	7	1
Jul 2023	8	7	8
Aug 2023	9	4	5
Sep 2023	6	7	4
Total	4194	4629	1111

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