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K469E allele of ICAM 1 is a candidate for susceptibility to IBD

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A genetic association study in Japanese patients has narrowed the probable site of a gene responsible for inflammatory bowel disease (IBD) to a region within the intercellular adhesion molecule 1 (ICAM 1) gene on chromosome 19p13.

The study found a significant overall association between the K469E polymorphism of the …

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