Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 −1082 promoter SNP and its interaction with TNF-α −308 promoter SNP

D Lio; L Scola; A Crivello; G Colonna-Romano; G Candore; M Bonafé; L Cavallone; F Marchegiani; F Olivieri; C Franceschi; C Caruso

doi:10.1136/jmg.40.4.296

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Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 −1082 promoter SNP and its interaction with TNF-α −308 promoter SNP

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	Abstract	Full	Pdf
Apr 2003	1	328	84
May 2003	0	209	63
Jun 2003	0	128	48
Jul 2003	0	128	23
Aug 2003	0	78	27
Sep 2003	0	65	27
Oct 2003	0	97	29
Nov 2003	0	45	13
Dec 2003	0	49	19
Jan 2004	0	47	18
Feb 2004	0	31	15
Mar 2004	0	31	11
Apr 2004	0	34	8
May 2004	0	56	9
Jun 2004	0	81	20
Jul 2004	1	79	34
Aug 2004	0	106	16
Sep 2004	0	113	27
Oct 2004	13	72	23
Nov 2004	17	81	29
Dec 2004	13	50	21
Jan 2005	16	81	63
Feb 2005	11	61	24
Mar 2005	12	66	41
Apr 2005	19	36	25
May 2005	9	32	21
Jun 2005	5	35	18
Jul 2005	4	23	21
Aug 2005	7	43	24
Sep 2005	5	67	27
Oct 2005	5	51	24
Nov 2005	7	42	18
Dec 2005	5	43	16
Jan 2006	4	38	14
Feb 2006	0	45	26
Mar 2006	2	49	26
Apr 2006	4	35	19
May 2006	4	28	17
Jun 2006	6	24	11
Jul 2006	4	34	13
Aug 2006	10	19	14
Sep 2006	4	21	14
Oct 2006	19	50	26
Nov 2006	6	26	14
Dec 2006	8	24	14
Jan 2007	24	34	117
Feb 2007	8	27	24
Mar 2007	17	26	22
Apr 2007	37	22	9
May 2007	30	13	12
Jun 2007	25	13	7
Jul 2007	21	14	7
Aug 2007	28	13	8
Sep 2007	21	13	7
Oct 2007	25	5	10
Nov 2007	20	11	9
Dec 2007	12	5	6
Jan 2008	19	7	6
Feb 2008	23	5	6
Mar 2008	25	12	9
Apr 2008	31	15	10
May 2008	8	0	2
Jun 2008	9	4	5
Jul 2008	18	6	3
Aug 2008	20	5	4
Sep 2008	15	6	4
Oct 2008	10	6	4
Nov 2008	22	5	3
Dec 2008	7	8	8
Jan 2009	13	4	3
Feb 2009	5	15	8
Mar 2009	18	5	4
Apr 2009	12	12	9
May 2009	29	8	3
Jun 2009	10	4	3
Jul 2009	14	3	4
Aug 2009	7	4	3
Sep 2009	7	1	3
Oct 2009	20	6	8
Nov 2009	21	5	5
Dec 2009	12	1	4
Jan 2010	13	1	3
Feb 2010	10	5	5
Mar 2010	26	2	1
Apr 2010	15	9	5
May 2010	13	5	4
Jun 2010	10	8	2
Jul 2010	11	13	7
Aug 2010	18	0	2
Sep 2010	9	5	5
Oct 2010	23	11	4
Nov 2010	13	7	3
Dec 2010	12	6	2
Jan 2011	10	2	0
Feb 2011	11	6	10
Mar 2011	19	8	3
Apr 2011	14	4	1
May 2011	15	3	1
Jun 2011	21	3	2
Jul 2011	19	3	4
Aug 2011	24	5	7
Sep 2011	18	4	4
Oct 2011	20	2	1
Nov 2011	23	8	9
Dec 2011	15	11	16
Jan 2012	14	9	10
Feb 2012	15	13	13
Mar 2012	16	13	9
Apr 2012	8	12	6
May 2012	7	14	10
Jun 2012	9	12	7
Jul 2012	16	17	10
Aug 2012	8	17	9
Sep 2012	22	11	8
Oct 2012	18	12	13
Nov 2012	0	16	10
Dec 2012	0	14	9
Jan 2013	0	20	8
Feb 2013	0	14	4
Mar 2013	0	10	13
Apr 2013	0	15	20
May 2013	0	20	13
Jun 2013	15	14	11
Jul 2013	13	6	8
Aug 2013	14	11	7
Sep 2013	12	40	6
Oct 2013	21	36	7
Nov 2013	14	22	13
Dec 2013	11	59	4
Jan 2014	13	27	11
Feb 2014	11	36	5
Mar 2014	17	35	7
Apr 2014	26	49	11
May 2014	25	28	7
Jun 2014	8	17	4
Jul 2014	19	27	10
Aug 2014	12	14	5
Sep 2014	20	6	5
Oct 2014	12	13	7
Nov 2014	16	5	6
Dec 2014	18	16	17
Jan 2015	14	5	4
Feb 2015	18	14	8
Mar 2015	26	19	10
Apr 2015	9	11	3
May 2015	19	12	4
Jun 2015	10	6	4
Jul 2015	9	5	1
Aug 2015	15	6	6
Sep 2015	14	5	3
Oct 2015	14	7	5
Nov 2015	10	8	3
Dec 2015	24	18	6
Jan 2016	22	9	5
Feb 2016	20	14	6
Mar 2016	15	12	6
Apr 2016	25	13	8
May 2016	23	9	5
Jun 2016	15	4	6
Jul 2016	20	3	5
Aug 2016	22	5	3
Sep 2016	10	8	3
Oct 2016	29	4	6
Nov 2016	42	4	2
Dec 2016	26	6	5
Jan 2017	31	8	3
Feb 2017	8	8	2
Mar 2017	8	16	4
Apr 2017	3	12	1
May 2017	4	16	2
Jun 2017	13	20	6
Jul 2017	15	8	5
Aug 2017	23	13	5
Sep 2017	31	25	2
Oct 2017	26	18	5
Nov 2017	29	21	3
Dec 2017	42	15	9
Jan 2018	32	18	7
Feb 2018	41	17	1
Mar 2018	23	11	3
Apr 2018	14	8	6
May 2018	23	10	4
Jun 2018	24	14	2
Jul 2018	20	12	5
Aug 2018	26	18	2
Sep 2018	28	20	10
Oct 2018	30	16	11
Nov 2018	23	16	7
Dec 2018	26	18	8
Jan 2019	34	24	4
Feb 2019	32	20	10
Mar 2019	29	28	6
Apr 2019	15	15	6
May 2019	28	28	9
Jun 2019	20	20	4
Jul 2019	21	16	13
Aug 2019	17	9	4
Sep 2019	31	19	19
Oct 2019	14	12	10
Nov 2019	26	19	5
Dec 2019	14	14	2
Jan 2020	30	20	5
Feb 2020	25	17	5
Mar 2020	19	15	4
Apr 2020	12	8	3
May 2020	19	16	4
Jun 2020	12	9	4
Jul 2020	16	10	3
Aug 2020	26	14	6
Sep 2020	24	18	9
Oct 2020	18	14	5
Nov 2020	32	16	19
Dec 2020	27	18	6
Jan 2021	25	15	6
Feb 2021	22	19	11
Mar 2021	44	30	14
Apr 2021	23	17	9
May 2021	16	16	9
Jun 2021	6	6	1
Jul 2021	9	8	5
Aug 2021	12	11	11
Sep 2021	13	12	8
Oct 2021	25	13	25
Nov 2021	16	8	21
Dec 2021	29	19	8
Jan 2022	61	43	9
Feb 2022	67	58	7
Mar 2022	66	60	5
Apr 2022	72	57	5
May 2022	85	79	15
Jun 2022	102	85	12
Jul 2022	70	64	5
Aug 2022	80	76	1
Sep 2022	77	73	9
Oct 2022	42	38	15
Nov 2022	88	78	10
Dec 2022	73	68	1
Jan 2023	93	81	9
Feb 2023	137	123	8
Mar 2023	107	99	9
Apr 2023	86	76	6
May 2023	82	79	12
Jun 2023	67	65	6
Jul 2023	56	52	7
Aug 2023	50	42	10
Sep 2023	42	24	6
Oct 2023	31	25	6
Nov 2023	29	15	3
Dec 2023	97	5	2
Jan 2024	89	1	1
Feb 2024	121	1	1
Mar 2024	107	2	0
Apr 2024	66	2	0
May 2024	80	1	0
Jun 2024	145	0	3
Jul 2024	78	0	0
Aug 2024	34	0	1
Sep 2024	41	1	2
Total	5972	6666	2586

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