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Susceptibility to Crohn’s disease may lurk in enzyme mutation

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A preliminary study of genetic polymorphisms affecting transforming enzymes in the gut has singled out for the first time microsomal epoxide hydrolase as a likely candididate for susceptibility to Crohn’s disease (CD).

Homozygous Tyr 113 substitution for His 113 in exon 3 of the microsomal epoxide hydrolase (EPXH) gene was …

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