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IBD5 risk haplotype and CARD15 variants add up to a bigger chance of Crohn’s disease

https://doi.org/10.1136/jmg.40.11.831

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    A genetic study has extended our understanding of susceptibility to Crohn’s disease, showing that the 5q31 (IBD5) cytokine cluster in British Caucasians does not interact with CARD15 variants and is rare in Japanese people. Nevertheless, potential genetic interactions still remain possible if variants in other …

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