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Prospective Belgian study of neurodegenerative and vascular dementia: APOE genotype effects
  1. S Engelborghs,
  2. B Dermaut,
  3. J Goeman,
  4. J Saerens,
  5. P Mariën,
  6. BA Pickut,
  7. M Van den Broeck,
  8. S Serneels,
  9. M Cruts,
  10. C Van Broeckhoven,
  11. P P De Deyn

    https://doi.org/10.1136/jmg.40.11.814

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      Objective: The authors conducted a prospective study of neurodegenerative and vascular dementia in Belgium. Strict diagnostic inclusion criteria were used to include well defined patients and controls. The results of apolipoprotein E (APOE) genotype effect on risk and clinical characteristics are presented.

      Methods: APOE genotyping was performed in patients with probable Alzheimer’s disease (AD) (n = 504), frontotemporal dementia (FTD) (n = 47), …

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